Almagro M, Pozo J D, Garcia J, Vasquez A, Fonseca E
Departments of Dermatology and Family Medicine, Hospital Juan Canalejo, Xubias de Arriba 84, 15006 La Coruña, Spain.
Eur J Dermatol. 2000 Mar;10(2):146-7.
Docetaxel and pactitaxel [corrected] are the main drugs pertaining to the taxanes family. Nail alterations associated with docetaxel therapy are not a rare event, but they have rarely been reported secondary to paclitaxel therapy, probably because of its more recent use. We present two cases of onycholysis and nail discoloration secondary to paclitaxel therapy.
多西他赛和紫杉醇是紫杉烷类家族的主要药物。与多西他赛治疗相关的指甲改变并非罕见事件,但继发于紫杉醇治疗的此类情况却鲜有报道,可能是因为紫杉醇使用时间较晚。我们报告两例继发于紫杉醇治疗的甲剥离和指甲变色病例。