Henderson R, Prince H
Department of Mathematics and Statistics, University of Lancaster, Lancaster LA1 4YF, UK.
Stat Med. 2000 Feb 29;19(4):563-74. doi: 10.1002/(sici)1097-0258(20000229)19:4<563::aid-sim356>3.0.co;2-k.
We consider bivariate survival problems in which interest is in the conditional distribution of one survival variable given an uncensored observation of the other. The work is motivated by an analysis of time to cancer diagnosis then subsequent survival amongst a group of organ transplant recipients. The effect of conditioning is illustrated for five standard bivariate models. The consequences of adopting a misspecified marginal approach in which the conditioning variable is considered to be a fixed covariate are investigated.
我们考虑双变量生存问题,其中关注点在于在对另一个变量有未删失观测值的情况下,一个生存变量的条件分布。这项工作的动机来自于对一组器官移植受者中癌症诊断时间以及后续生存情况的分析。针对五个标准双变量模型说明了条件作用的效果。研究了采用错误设定的边际方法(即将条件变量视为固定协变量)的后果。