Richter J E
Department of Gastroenterology, Cleveland Clinic Foundation, Ohio, USA.
Gastroenterol Clin North Am. 1999 Dec;28(4):875-91, vi. doi: 10.1016/s0889-8553(05)70095-9.
Peptic esophageal strictures occur in the context of inadequately treated gastroesophageal reflux, especially in elderly patients. Studies show more pronounced abnormalities of esophageal function resulting in an increased number of prolonged reflux episodes. The diagnosis is best made by a combination of barium esophagram and endoscopy. Patients usually require esophageal dilation to relieve dysphagia followed by adequate medical therapy. Proton pump inhibitors are effective for preventing the recurrence of strictures after dilation. In young patients and patients with strictures that are difficult to dilate or need frequent dilations, surgery may be required; however, results can be disappointing.
消化性食管狭窄发生于胃食管反流治疗不充分的情况下，尤其是老年患者。研究表明食管功能存在更明显的异常，导致长时间反流发作次数增加。最佳诊断方法是结合食管钡餐造影和内镜检查。患者通常需要进行食管扩张以缓解吞咽困难，随后进行充分的药物治疗。质子泵抑制剂对预防扩张后狭窄复发有效。对于年轻患者以及狭窄难以扩张或需要频繁扩张的患者，可能需要手术治疗；然而，手术结果可能不尽人意。
