Hryszko T, Małyszko J, Myśliwiec M
Kliniki Nefrologii i Chorób Wewnetrznych, Akademii Medycznej w Białymstoku.
Przegl Lek. 1999;56(9):599-603.
Both bleeding and thrombosis may complicate the course of chronic uremia. The main cause of bleeding diathesis is a dysfunction of the primary hemostasis. The widespread improvement of conservative and substitutive therapy has considerably ameliorated the frequency of hemorrhagic complications in uremic patients. The aim of the study review modern views on pathogenesis of bleeding diathesis with particular attention paid to the role of platelets, as well as diagnostic and therapeutic possibilities.
出血和血栓形成都可能使慢性尿毒症的病程复杂化。出血素质的主要原因是初级止血功能障碍。保守治疗和替代治疗的广泛改进已大大降低了尿毒症患者出血并发症的发生率。本研究的目的是回顾关于出血素质发病机制的现代观点,特别关注血小板的作用以及诊断和治疗的可能性。