Ayoola E A, Nanda V J, Gadour M O, Elamin A K
Department of Gastroenterology, King Fahd Central Hospital, Gizan, Kingdom of Saudi Arabia.
Trop Gastroenterol. 1999 Jul-Sep;20(3):137-9.
In contrast to the experience in the adults, there are limited data concerning the efficacy and safety of upper gastrointestinal endoscopy (UGIE) in paediatric patients. The information on this procedure is very scanty from non-western countries. We analysed 72 children evaluated in Gizan, Saudi Arabia, an area of high endemic hepatitis B and chronic liver disease. The indications comprised abdominal pain (49%), UGI bleeding (24%) and evaluation of suspected portal hypertension. No abnormality was detected in 33 (46%). Mucosal inflammatory lesions (oesophagitis, gastritis and duodenitis) are the commonest abnormal lesions, occurring in 24 (33%). Duodenal ulcer (4 cases) and gastric ulcer (1 case) were relatively few. No case of malignancy was found. Sclerotherapy for variceal bleeding was effective in 4 patients. Helicobacter pylori was detected in 12 of 23 patients and associated with histologically identified gastritis in the majority of these cases. It is concluded that paediatric UGIE is safe and useful in the diagnosis and therapeutic intervention for UGI diseases in children. Our findings provide additional information on the pattern of diseases among Saudi Arabian children.
与成人的经验相比，关于上消化道内镜检查（UGIE）在儿科患者中的疗效和安全性的数据有限。来自非西方国家的关于该检查的信息非常匮乏。我们分析了在沙特阿拉伯吉赞接受评估的72名儿童，该地区是乙型肝炎和慢性肝病的高流行区。检查指征包括腹痛（49%）、上消化道出血（24%）以及对疑似门静脉高压的评估。33例（46%）未发现异常。黏膜炎症性病变（食管炎、胃炎和十二指肠炎）是最常见的异常病变，有24例（33%）。十二指肠溃疡（4例）和胃溃疡（1例）相对较少。未发现恶性肿瘤病例。4例患者的静脉曲张出血硬化治疗有效。23例患者中有12例检测到幽门螺杆菌，在大多数这些病例中，幽门螺杆菌与组织学确诊的胃炎相关。结论是儿科上消化道内镜检查在儿童上消化道疾病的诊断和治疗干预中是安全且有用的。我们的研究结果提供了关于沙特阿拉伯儿童疾病模式的更多信息。
