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在管理式医疗环境中优化冠状动脉疾病患者的血脂异常治疗(落基山凯撒医疗机构的经验)

Optimizing treatment of dyslipidemia in patients with coronary artery disease in the managed-care environment (the Rocky Mountain Kaiser Permanente experience).

作者信息

Merenich J A, Lousberg T R, Brennan S H, Calonge N B

机构信息

Department of Endocrinology, Rocky Mountain Kaiser Permanente, Denver, Colorado 80205, USA.

出版信息

Am J Cardiol. 2000 Feb 10;85(3A):36A-42A. doi: 10.1016/s0002-9149(99)00937-6.

Abstract

Rocky Mountain Kaiser Permanente has taken aggressive steps to ensure optimal treatment of all modifiable cardiac risk factors, especially low-density lipoprotein (LDL) cholesterol, in patients with coronary artery disease. In this article, we are presenting (1) the basic rationale for our approach, (2) the critical steps translating philosophy into practice, and (3) justification for all health plans to pursue a similar course. The continuum of physician-directed disease management systems that have evolved in our region-one administered by cardiology nurses in the perihospitalization period and the other by pharmacists in the long-term, outpatient setting-is then detailed. Although the relatively short duration that our comprehensive systems have been in place precludes any assessment of their impact on cardiac death, coronary artery disease events, or coronary artery disease procedure rates, the improvements in intermediate surrogate outcomes are promising. Virtually all surveyed patients participating in our management systems have been "very" or "extremely" satisfied with their experience. The LDL-cholesterol screening rate in the approximately 2,500 participants in the programs to date has reached 97%. Of these patients, 84% have LDL cholesterol <130 mg/dL and 48% <100 mg/dL, and only 15% of those few with LDL cholesterol >130 mg/dL (2.5% overall) are currently not receiving lipid-lowering therapy. The proportions of patients on aspirin/antiplatelet and beta-blocker therapy after myocardial infarction are 97% and 92%, respectively. The lipid-screening and treatment rates, especially, represent significant improvement from our own baseline, and compare favorably with outcomes from other practice settings. In conclusion, health maintenance organizations have tremendous incentive and the unique opportunity and ability to develop systems to better manage large numbers of individuals with coronary artery disease.

摘要

落基山凯撒医疗集团已采取积极措施,确保对所有可改变的冠心病风险因素进行最佳治疗,尤其是低密度脂蛋白(LDL)胆固醇。在本文中,我们将介绍:(1)我们采取该方法的基本原理;(2)将理念转化为实践的关键步骤;(3)所有健康计划采取类似做法的理由。接着详细阐述了在我们地区逐步发展起来的由医生主导的疾病管理系统的连续统一体——一个由心脏病护理人员在住院期间管理,另一个由药剂师在长期门诊环境中管理。尽管我们的综合系统实施时间相对较短,无法评估其对心脏死亡、冠心病事件或冠心病手术率的影响,但中间替代指标的改善前景良好。几乎所有参与我们管理系统的受访患者对他们的体验都“非常”或“极其”满意。到目前为止,在该项目约2500名参与者中,LDL胆固醇筛查率已达到97%。在这些患者中,84%的患者LDL胆固醇<130mg/dL,48%<100mg/dL,而在那些LDL胆固醇>130mg/dL的少数患者中(总体占2.5%),目前只有15%未接受降脂治疗。心肌梗死后接受阿司匹林/抗血小板和β受体阻滞剂治疗的患者比例分别为97%和92%。尤其是血脂筛查和治疗率,与我们自己的基线相比有显著提高,并且与其他医疗机构的结果相比也更具优势。总之,健康维护组织有巨大的动力,也有独特的机会和能力来开发系统,以更好地管理大量冠心病患者。

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