一例犬慢性粒细胞白血病病例。

Joiner G N, Fraser C J, Jardin J H, Trujillo J M

Can J Comp Med. 1976 Apr;40(2):153-60.

A case of chronic granulocytic leukemia was diagnosed in a ten year old miniature poodle and was observed for four and one half years. Methods of diagnosis and characteristic features are described. A persistent granulocytosis with a preponderance of mature forms and the absence of a detectable underlying pyogenic process were key diagnostic features which enabled distinction of this neoplastic process from acute granylocytic leukemia and a leukemoid reaction. Other features included dysplastic granulocytes in various developmental stages, marginal anemia and hyperplastic bone marrow (myeloid elements). No blast crisis occurred. This dog was euthanatized in August 1975.

一只10岁的迷你贵宾犬被诊断出患有慢性粒细胞白血病，并被观察了四年半。文中描述了诊断方法和特征。持续的粒细胞增多，以成熟形式为主，且未发现潜在的化脓性过程，这些是关键的诊断特征，可将这种肿瘤性疾病与急性粒细胞白血病和类白血病反应区分开来。其他特征包括不同发育阶段的发育异常粒细胞、边缘性贫血和骨髓增生（髓系成分）。未发生急变期。这只狗于1975年8月实施了安乐死。