Drug Ther Bull. 1999 Oct;37(10):73-7. doi: 10.1136/dtb.1999.371073.
In the UK around 1 in 5 children will have been diagnosed as having asthma at some stage before they reach 15 years old. The use of inhaled corticosteroids has done much to reduce morbidity in these children and current British Guidelines recommend the use of inhaled corticosteroids in all but mild childhood asthma. However, there are concerns about the long-term safety of such treatment in growing children, and the benefits and risks of their use need careful evaluation. In this article we review the place of inhaled corticosteroids in childhood asthma.
在英国,约五分之一的儿童在15岁之前的某个阶段会被诊断出患有哮喘。吸入性糖皮质激素的使用在很大程度上降低了这些儿童的发病率,目前英国的指南建议,除轻度儿童哮喘外,所有儿童哮喘均应使用吸入性糖皮质激素。然而,人们担心这种治疗方法对正在成长的儿童的长期安全性,其使用的益处和风险需要仔细评估。在本文中,我们将综述吸入性糖皮质激素在儿童哮喘治疗中的地位。