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地夫可特——泼尼松龙的替代品?

Deflazacort--an alternative to prednisolone?

出版信息

Drug Ther Bull. 1999 Aug;37(8):57-8. doi: 10.1136/dtb.1999.37857.

DOI:10.1136/dtb.1999.37857
PMID:10696685
Abstract

Deflazacort (Calcort--Shire) is an oral corticosteroid licensed for use in adults and children. When deflazacort first became available last year, the manufacturer claimed that the drug had a lower incidence of steroid-induced unwanted effects compared with prednisolone. However, this claim was later withdrawn at the request of the Medicines Control Agency following its review of the cited data. Current promotional material claims simply that deflazacort is "a new choice of oral steroid". Here we discuss whether deflazacort offers any advantages over established corticosteroid therapy.

摘要

地夫可特(Calcort--施贵宝公司)是一种口服皮质类固醇药物,已获许可用于成人和儿童。去年地夫可特首次上市时,制造商声称与泼尼松龙相比,该药物引起类固醇不良反应的发生率较低。然而,在药品管理局对引用数据进行审查后,这一说法随后应其要求被撤回。目前的促销材料仅称地夫可特是“口服类固醇的一种新选择”。在此,我们讨论地夫可特是否比既定的皮质类固醇疗法具有任何优势。

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Deflazacort--an alternative to prednisolone?地夫可特——泼尼松龙的替代品?
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Deflazacort.地夫可特
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Deflazacort. A review of its pharmacological properties and therapeutic efficacy.地夫可特。其药理特性与治疗效果综述。
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Deflazacort: towards selective glucocorticoid receptor modulation?
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A longterm prospective study of the equipotency between deflazacort and prednisolone in the treatment of patients with polymyalgia rheumatica.一项关于地夫可特与泼尼松龙治疗风湿性多肌痛患者等效性的长期前瞻性研究。
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Comparison of the pharmacodynamic effects of deflazacort and prednisolone in healthy subjects.去氟可特与泼尼松龙在健康受试者中的药效学作用比较。
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Corticosteroid therapy for nephrotic syndrome in children.儿童肾病综合征的皮质类固醇疗法。
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Deflazacort in comparison to other steroids for nephrotic syndrome.与其他用于治疗肾病综合征的类固醇相比,地夫可特的情况。
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