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一名儿童因误食蓖麻子而导致肝毒性。

Hepatotoxicity from castor bean ingestion in a child.

作者信息

Palatnick W, Tenenbein M

机构信息

University of Manitoba, Winnipeg, Canada.

出版信息

J Toxicol Clin Toxicol. 2000;38(1):67-9. doi: 10.1081/clt-100100920.

Abstract

BACKGROUND

Castor beans contain ricin, one of the most toxic substances known. A biphasic toxicity is described consisting of acute and potentially fatal gastroenteritis followed by damage to the viscera several days later. However, the most current review of the literature states that the above delayed toxicity has not been reported.

CASE REPORT

We report a 20-month-old girl with no gastrointestinal symptoms who developed reversible hepatotoxicity beginning 48-72 hours after the ingestion of castor beans.

CONCLUSION

It seems prudent to follow for several days any patients who actually chewed castor beans before ingestion.

摘要

背景

蓖麻子含有蓖麻毒素,这是已知的最有毒物质之一。其毒性呈双相性,包括急性且可能致命的肠胃炎,随后在数天后出现内脏损伤。然而,最新的文献综述指出,上述延迟毒性尚未见报道。

病例报告

我们报告一名20个月大的女童,在摄入蓖麻子后48 - 72小时开始出现可逆性肝毒性,摄入前无胃肠道症状。

结论

对于任何实际咀嚼过蓖麻子再摄入的患者,持续观察数天似乎是谨慎的做法。

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