Pikoulis E, Rhee P, Nishibe T, Burris D, Leppäniemi A K, Fishback N, Wherry D C, Rich N M
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
J Trauma. 2000 Feb;48(2):292-5. doi: 10.1097/00005373-200002000-00016.
Vascular closure staple (VCS) clips made of titanium were originally developed for microvascular anastomoses. There is limited experience with their applicability to vascular reconstruction in larger vessels. This study compares VCS clips to standard sutures in arterial repair using a synthetic patch.
In an experimental study with pigs, two sequential 10-mm abdominal aortotomies were allocated randomly to synthetic patch (polytetrafluoroethylene) repair with VCS clips or continuous 6-0 polypropylene sutures. Angiographic, macroscopic, and microscopic results were assessed after 2 months.
There were no significant differences in the patency rate, vessel diameter at the repair site, or healing indices. The mean (SD) clamp time was 8.7 (3.0) minutes for clip repair and 14.3 (7.4) minutes for suture repair (p = 0.04), and the times required for the vessel reconstruction were 5.3 (1.3) and 9.3 (3.0) minutes, respectively (p = 0.009).
Patched arterial repair with VCS clips is faster than sutured reconstruction with comparable results after 2 months of follow up.
由钛制成的血管闭合吻合钉（VCS）最初是为微血管吻合而开发的。其在较大血管的血管重建中的适用性经验有限。本研究比较了在使用合成补片进行动脉修复时VCS吻合钉与标准缝线的效果。
在一项针对猪的实验研究中，将两个连续的10毫米腹主动脉切开随机分配为用VCS吻合钉进行合成补片（聚四氟乙烯）修复或用连续6-0聚丙烯缝线修复。2个月后评估血管造影、宏观和微观结果。
在通畅率、修复部位的血管直径或愈合指数方面没有显著差异。吻合钉修复的平均（标准差）夹闭时间为8.7（3.0）分钟，缝线修复为14.3（7.4）分钟（p = 0.04），血管重建所需时间分别为5.3（1.3）和9.3（3.0）分钟（p = 0.009）。
在随访2个月后，用VCS吻合钉进行补片动脉修复比缝线重建更快，且结果相当。
