特应性和哮喘遗传易感性的种族差异。

Ethnic differences in genetic susceptibility to atopy and asthma.

作者信息

Tay A H, Tan E C, Chew F T, Goh D L, Shek L P, Lee B W

机构信息

Department of Paediatrics, National University of Singapore, Singapore.

出版信息

Asian Pac J Allergy Immunol. 1999 Sep;17(3):239-42.

PMID:10697264

Abstract

The genetics of asthma and atopy is complex, but can be approached by studies of both candidate genes and mapping of susceptibility loci. Genetic factors conferring susceptibility to disease may vary among ethnic groups. We present our experience with some candidate gene studies for asthma and atopy and susceptibility locus mapping for linkage to chromosome 5q.

摘要

哮喘和特应性的遗传学很复杂，但可以通过对候选基因的研究以及易感基因座的定位来进行探讨。导致易患疾病的遗传因素在不同种族群体中可能有所不同。我们介绍了我们在一些哮喘和特应性候选基因研究以及与5号染色体q臂连锁的易感基因座定位方面的经验。