Garcia-Cimbrelo E, Diaz-Martin A, Madero R, Munera L
Department of Orthopaedics, Hospital la Paz, Universidad Autónoma de Madrid, Spain.
J Bone Joint Surg Br. 2000 Jan;82(1):108-15. doi: 10.1302/0301-620x.82b1.9796.
Between 1972 and 1990, we performed 168 primary low-friction arthroplasties in 125 patients with acetabular protrusion. Twelve hips were lost to follow-up within eight years and eight which became infected were excluded from the final study. Of the 148 hips remaining, 62 with a mild protrusion were classified as group 1, 54 with moderate or severe protrusion as group 2 and, after 1985, 32 with moderate and severe protrusion which required bone grafts as group 3. The mean follow-up was 18.3 years (3 to 24) for group 1, 17.4 years (8 to 22) for group 2 and ten years (8 to 13) for group 3. There were 31 revisions of the cup, 12 in group 1 and 19 in group 2. According to the Kaplan-Meier analysis the overall rates at 20 years were 21 +/-10.79% in group 1 and 37 +/- 11.90% in group 2. There have been 43 radiological loosenings: 22 in group 1, 21 in group 2 and none so far in group 3, at ten years. The overall loosening rates at 20 years were 42 +/-14.76% in group 1 and 49 +/- 19.50% in group 2. The grafts were well incorporated in all group-3 hips, and the bone structure appeared normal after one year. The distance between the centre of the head of the femoral prosthesis and the approximate true centre of the femoral head was less in group 3 than in groups 1 and 2 (p < 0.01). According to the Cox proportional-hazards regression this was the single most important factor in loosening of the cup (odds ratio 1.11; 95% CI 1.05 to 1.18/mm). Better results were obtained in moderate and severe protrusions reconstructed with bone grafting than in hips with mild protrusion which were not grafted.
1972年至1990年间,我们对125例髋臼前突患者实施了168例初次低摩擦关节成形术。12例髋关节在8年内失访,8例发生感染的患者被排除在最终研究之外。在剩余的148例髋关节中,62例轻度前突的患者被归为第1组,54例中度或重度前突的患者为第2组,1985年后,32例需要植骨的中度和重度前突患者为第3组。第1组的平均随访时间为18.3年(3至24年),第2组为17.4年(8至22年),第3组为10年(8至13年)。髋臼翻修31例,第1组12例,第2组19例。根据Kaplan-Meier分析,20年时第1组的总体翻修率为21±10.79%,第2组为37±11.90%。有43例发生影像学松动:第1组22例,第2组21例,第3组在10年时目前尚无松动病例。20年时第1组的总体松动率为42±14.76%,第2组为49±19.50%。第3组所有髋关节的移植骨均融合良好,1年后骨结构看起来正常。第3组股骨假体股骨头中心与股骨头大致真实中心之间的距离小于第1组和第2组(p<0.01)。根据Cox比例风险回归分析,这是髋臼松动的唯一最重要因素(优势比1.11;95%可信区间1.05至1.18/mm)。采用植骨重建的中度和重度前突患者比未植骨的轻度前突患者效果更好。