Yapp Liam Z, Clement Nick D, Scott Chloe E H, Ng Nathan, Breusch Hanna P, MacDonald Deborah J, Gaston Paul, Breusch Steffen J
Department of Trauma & Orthopaedic Surgery, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SY, UK.
Division of Clinical and Surgical Sciences, Department of Orthopaedics, University of Edinburgh, Chancellors Building, 49 Little France Cres, Edinburgh EH16 4SB, UK.
J Clin Med. 2024 Sep 21;13(18):5612. doi: 10.3390/jcm13185612.
: This study reports the long-term survivorship of primary total hip arthroplasty (THA) for protrusio acetabuli. : Patients undergoing THA utilising cement and bone graft acetabular reconstruction for protrusio acetabuli in a university teaching hospital during the period 2003 to 2014 were included. Kaplan-Meier survival estimates were calculated with 95% confidence intervals (CI) up to 15 years following surgery. PROMs were collected pre- and post-operatively for hip-specific function (Oxford Hip Score [OHS]) and health-related quality of life (HRQoL) using the EQ-5D-3L. : 129 consecutive THAs (96 patients) performed for protrusio acetabuli were identified (median age 69, IQR 61-75; female 115 [89.1%]; 38 [29.5%] inflammatory arthritis) with a mean follow-up of 15.7 years (range: 10.1-20.1 years). At the final follow-up, fifty-six (43.4%) patients had died and there were eleven (8.5%) reoperations, of which eight (6.2%) involved the revision of the acetabular component. The fifteen-year Kaplan-Meier any-reoperation survival estimate was 91.3% (95% CI 85.9-97.0). When considering all-cause acetabular revision only, the 15-year survival estimate was 93.1% (95% CI 88.2-98.3). The median pre-operative OHS improved significantly from baseline to 1 year post-THA, beyond the minimal important change (mean difference 28, 95% CI 25-30, < 0.001). Similarly, there were clinically relevant improvements in HRQoL at 1 year post surgery (mean difference 0.10, 95% CI 0.06-0.15, < 0.001). : This study demonstrates that primary cemented THA utilising acetabular bone graft for reconstruction in patients with protrusio acetabuli was associated with 15-year survival rates of 93.1% and clinically relevant improvements in hip-specific function and HRQoL.
本研究报告了髋臼前突患者初次全髋关节置换术(THA)的长期生存率。纳入2003年至2014年期间在某大学教学医院接受采用骨水泥和植骨进行髋臼重建的髋臼前突THA手术的患者。计算Kaplan-Meier生存估计值及术后15年的95%置信区间(CI)。术前和术后使用EQ-5D-3L收集髋关节特定功能(牛津髋关节评分[OHS])和健康相关生活质量(HRQoL)的患者报告结局测量(PROMs)。共确定了129例连续进行的髋臼前突THA手术(96例患者)(中位年龄69岁,四分位间距61 - 75岁;女性115例[89.1%];38例[29.5%]为炎性关节炎),平均随访15.7年(范围:10.1 - 20.1年)。在最后一次随访时,56例(43.4%)患者死亡,11例(8.5%)进行了再次手术,其中8例(6.2%)涉及髋臼组件翻修。15年的Kaplan-Meier再次手术生存估计值为91.3%(95%CI 85.9 - 97.0)。仅考虑因各种原因进行的髋臼翻修时,15年生存估计值为93.1%(95%CI 88.2 - 98.3)。术前OHS中位数从基线到THA术后1年显著改善,超过最小重要变化(平均差值28,95%CI 25 - 30,<0.001)。同样,术后1年HRQoL有临床相关改善(平均差值0.10,95%CI 0.06 - 0.15,<0.001)。本研究表明,对于髋臼前突患者采用髋臼植骨进行初次骨水泥THA手术,其15年生存率为93.1%,且髋关节特定功能和HRQoL有临床相关改善。