Maćkowski J, Niemczyk S, Matuszkiewicz-Rowińska J, Gomółka M
I Oddział Chorób Wewnetrznych ze Stacja Dializ, Warszawie.
Pol Arch Med Wewn. 1999 Mar;101(3):237-40.
In two patients with end stage renal failure and not treated diabetes spontaneous hypoglycaemiaes were observed. The lowest levels of glucose in blood serum were: 1.9 mmol/L and 1.16 mmol/L. These levels were accompanied by symptoms of severe neuroglycopenia. Despite of intensive pharmacological treatment recurrent hypoglycaemia episodes appeared for 34 hours in one case and 32 hours in the other. Authors discussed pathophysiological processes leading to hypoglycaemia in end stage renal failure patients. It seems that disturbances in renal gluconeogenesis together with lower degradation of insulin played the key role in creating hypoglycaemia in those two patients.
在两名终末期肾衰竭且未接受糖尿病治疗的患者中观察到自发性低血糖。血清葡萄糖的最低水平分别为：1.9毫摩尔/升和1.16毫摩尔/升。这些水平伴有严重低血糖的症状。尽管进行了强化药物治疗，但其中一例反复出现低血糖发作持续34小时，另一例持续32小时。作者讨论了导致终末期肾衰竭患者低血糖的病理生理过程。似乎肾脏糖异生的紊乱以及胰岛素降解降低在这两名患者低血糖的发生中起了关键作用。
