Dalsgarth O J, Vestbo J, Lange P
Lungemedicinsk klinik, H:S Hvidovre hospital.
Ugeskr Laeger. 2000 Jan 24;162(4):529-32.
Corticosteroids are widely used as first-line drugs in the treatment of patients with exacerbation of COPD. Until recently the scientific evidence has been scarce and generally taken from the treatment of asthma. In this article we interpret the results of the available prospective studies on corticosteroid treatment in exacerbation of COPD and suggest guidelines regarding the clinical handling of COPD patients in matter of dose, form of administration and duration of treatment.
皮质类固醇被广泛用作慢性阻塞性肺疾病(COPD)急性加重期患者的一线治疗药物。直到最近,相关科学证据仍很匮乏,且大多取自哮喘治疗的研究。在本文中,我们解读了关于皮质类固醇治疗COPD急性加重期的现有前瞻性研究结果,并就COPD患者在剂量、给药方式及治疗持续时间方面的临床处理提出指导建议。