Abu Shaqra Q
Medical Diagnostic Laboratories, Zarka, Jordan.
Cytobios. 2000;101(396):15-21.
The type and antibiotic sensitivity of urinary tract pathogens may differ in various communities. Of 207 isolates recovered from midstream urine specimens collected from a group of patients with community acquired urinary tract infections (UTI), 86% were species of Enterobacteriaceae. The most frequently recovered pathogens were Escherichia coli (82%), Klebsiella spp. (7.3%), Proteus spp. (6.2%), Enterobacter spp. (3.4%) and Citrobacter spp. (1.1%). High rates of resistance were found against ampicillin (95%), tetracycline (86%), carbenicillin (84%), trimethoprim/sulphamethoxazole (48%), and amoxycillin/clavulanic acid (45%). For the antibiotics tobramycin, aztreonam, ceftriaxone and gentamicin 7% of the isolates were resistant, while resistance varied from 9-18% for amikacin, ciprofloxacin, norfloxacin, nalidixic acid and cefuroxime. The incidence of UTI caused by Enterobacteriaceae was three times higher in females than in males, particularly in young and middle age groups (< or = 19 and 20-39 years).
不同社区尿路病原体的类型和抗生素敏感性可能有所不同。从一组社区获得性尿路感染(UTI)患者的中段尿标本中分离出的207株菌株中,86%为肠杆菌科菌种。最常分离出的病原体是大肠杆菌(82%)、克雷伯菌属(7.3%)、变形杆菌属(6.2%)、肠杆菌属(3.4%)和柠檬酸杆菌属(1.1%)。发现对氨苄西林(95%)、四环素(86%)、羧苄西林(84%)、甲氧苄啶/磺胺甲恶唑(48%)和阿莫西林/克拉维酸(45%)的耐药率很高。对于抗生素妥布霉素、氨曲南、头孢曲松和庆大霉素,7%的分离株耐药,而阿米卡星、环丙沙星、诺氟沙星、萘啶酸和头孢呋辛的耐药率在9%-18%之间。女性由肠杆菌科引起的UTI发病率是男性的三倍,尤其是在年轻和中年组(≤19岁和20-39岁)中。