Puntis J W, Thwaites R, Abel G, Stringer M D
University of Leeds, The General Infirmary at Leeds, Neonatal Unit, UK.
Dev Med Child Neurol. 2000 Feb;42(2):97-9. doi: 10.1017/s0012162200000190.
Whether antireflux surgery should be routinely performed at the time of gastrostomy in children with neurological disorders is debatable because of the risk of gastroesophageal reflux. Some argue that these children should be screened for occult gastroesophageal reflux as this will determine the need for fundoplication. This study retrospectively examines outcome in 29 children with neurological disorders who underwent percutaneous endoscopic gastrostomy (PEG) without concomitant fundoplication. Children were included if they had no clinical evidence of severe gastroesophageal reflux before PEG insertion. The median age of children at PEG insertion was 5.6 years (range 1.1 to 18.0). The children were followed for a median of 2.6 years (range 0.4 to 4.9). Insertion of PEG was technically impossible in two children; and an asymptomatic gastrocolic fistula in another child led to subsequent tube removal. Fourteen of the 26 remaining children developed symptomatic gastroesophageal reflux after PEG; five of these showed no reflux on pH monitoring prePEG. Control of symptoms was achieved by medical intervention in 12, but two required fundoplication. Our findings indicate that in the child with neurological disabilities without symptoms indicating severe gastroesophageal reflux, fundoplication is unlikely to be necessary as a consequence of PEG insertion. We conclude that routine investigation for gastroesophageal reflux in the child without severe vomiting can be avoided and the number of antireflux procedures reduced.
对于患有神经系统疾病的儿童,在进行胃造瘘术时是否应常规进行抗反流手术存在争议,因为存在胃食管反流的风险。一些人认为这些儿童应接受隐匿性胃食管反流筛查,因为这将决定是否需要进行胃底折叠术。本研究回顾性分析了29例患有神经系统疾病且未同时进行胃底折叠术的儿童经皮内镜下胃造瘘术(PEG)的结果。如果儿童在PEG插入前没有严重胃食管反流的临床证据,则纳入研究。PEG插入时儿童的中位年龄为5.6岁(范围1.1至18.0岁)。对儿童进行了中位2.6年的随访(范围0.4至4.9年)。两名儿童技术上无法进行PEG插入;另一名儿童出现无症状胃结肠瘘,导致随后拔除胃管。其余26名儿童中有14名在PEG后出现症状性胃食管反流;其中5名在PEG前pH监测时未显示反流。12名儿童通过药物干预控制了症状,但有两名儿童需要进行胃底折叠术。我们的研究结果表明,对于没有症状提示严重胃食管反流的神经功能障碍儿童,由于PEG插入而进行胃底折叠术不太可能是必要的。我们得出结论,对于没有严重呕吐的儿童,可以避免常规的胃食管反流检查,并减少抗反流手术的数量。