Cohen D, Taieb O, Flament M, Benoit N, Chevret S, Corcos M, Fossati P, Jeammet P, Allilaire J F, Basquin M
Department of Child and Adolescent Psychiatry, Groupe Hospitalier Pitié-Salpétrière, Paris, France.
Am J Psychiatry. 2000 Mar;157(3):460-2. doi: 10.1176/appi.ajp.157.3.460.
Cognitive functions of adolescents treated with ECT for mood disorder were evaluated at long-term follow-up.
At an average of 3.5 years (SD=1.7) after the last ECT, 10 subjects treated during adolescence with bilateral ECT for severe mood disorder completed a clinical and cognitive evaluation, including the California Verbal Learning Test and Squire's Subjective Memory Questionnaire. The same assessments were given to 10 psychiatric comparison subjects matched for sex, age, and diagnosis.
All cognitive test scores of the patients treated with ECT were similar to those of the comparison subjects and did not differ from norms from the community. Six of the 10 ECT-treated patients reported having had memory losses immediately after the ECT course, but only one complained of subjective memory impairment at follow-up.
The results suggest that adolescents given ECT for severe mood disorder do not suffer measurable cognitive impairment at long-term follow-up.
在长期随访中评估接受电休克治疗（ECT）的青少年情绪障碍患者的认知功能。
在最后一次ECT治疗平均3.5年（标准差=1.7）后，10名在青少年期接受双侧ECT治疗严重情绪障碍的受试者完成了临床和认知评估，包括加利福尼亚言语学习测试和斯夸尔主观记忆问卷。对10名在性别、年龄和诊断方面匹配的精神科对照受试者进行了相同的评估。
接受ECT治疗的患者所有认知测试分数与对照受试者相似，且与社区常模无差异。10名接受ECT治疗的患者中有6名报告在ECT疗程后立即出现记忆丧失，但随访时只有1名抱怨有主观记忆损害。
结果表明，接受ECT治疗严重情绪障碍的青少年在长期随访中未出现可测量的认知损害。
