培养的心脏细胞由胆碱能神经元内源性来源进行神经支配。
Innervation of heart cells in culture by an endogenous source of cholinergic neurons.
作者信息
Lane M A, Sastre A, Salpeter M M
出版信息
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4506-10. doi: 10.1073/pnas.73.12.4506.
Abstract
Hearts of embryonic mice 9 days in utero were found to have an endogenous source of cholinergic neurons which can survive in dispersed cell cultures. These neurons are electrically excitable, have ultrastructural characteristics of cholinergic embryonic neurons, and functionally innervate heart cells in culture. The nature of the innervation described is muscarinic cholinergic.
摘要
在子宫内发育9天的胚胎小鼠心脏中，发现有胆碱能神经元的内源性来源，这些神经元在分散的细胞培养物中能够存活。这些神经元具有电兴奋性，具有胆碱能胚胎神经元的超微结构特征，并在功能上支配培养中的心脏细胞。所述神经支配的性质是毒蕈碱型胆碱能。
Zotero 插件