Lele M V, Joglekar A S
Department of Psychiatry, Seth G.S. Medical College, Mumbai.
J Postgrad Med. 1998 Apr-Jun;44(2):50-5.
Poor insight in schizophrenia has been recently thought to be a reflection of prominent and enduring neurocognitive impairments. Reports supporting this theory have implicated prefrontal and parietal lobe functions, among other parameters. The results of other studies have negated the role of neuropsychological abnormalities in poor insight. The analogy between poor insight in schizophrenia and anosognosia in neurological illness as proposed by one set of workers has been elucidated in this review and it appears quite promising. However, the drawing of definite conclusions from all this work has been deferred by us, because of the need for more uniform and standardized methodologies for research on the subject. Nevertheless, attempts to improve the cognitive processes, which affect insight in schizophrenia, may be done to gain better treatment outcome in this disorder.
近期，精神分裂症患者的自知力缺失被认为是显著且持久的神经认知障碍的一种反映。支持这一理论的报告涉及前额叶和顶叶功能等多个参数。其他研究结果则否定了神经心理异常在自知力缺失中的作用。一组研究人员提出的精神分裂症自知力缺失与神经疾病中疾病感缺失之间的类比在本综述中得到了阐释，且看起来颇具前景。然而，由于需要更统一和标准化的研究方法来研究该主题，我们暂未从所有这些研究中得出明确结论。尽管如此，为改善影响精神分裂症自知力的认知过程所做的尝试，或许有助于在这种疾病中获得更好的治疗效果。
