Carreno C A, King M, Johnson M P, Yaron Y, Diamond M P, Bush D, Evans M I
Department of Obstetrics, Wayne State University, Detroit, Mich., USA.
Fetal Diagn Ther. 2000 Jan-Feb;15(1):1-3. doi: 10.1159/000020967.
To find a suitable technique to selectively terminate a cervically implanted embryo while maintaining viability of a concomitant intrauterine pregnancy.
A 34-year-old patient achieved a twin pregnancy after 4 IVF attempts. Ultrasound revealed a viable intrauterine and cervical pregnancy. Given our experience with KCl injection for fetal reduction, we offered the patient an attempt to reduce the cervical pregnancy.
Best visualization in this case was obtained by transabdominal scanning. A 6-inch 20-gauge spinal needle was inserted transcervically and maneuvered into the thorax of the embryo. Fetal heart rate ceased even before KCl could be injected. Then 3 cm(3) of saline were injected to provide better visualization of the cervical fetus, and to confirm absence of heart beat. The patient had minor vaginal bleeding for several days. The intrauterine pregnancy progressed uneventfully through 36(1)/(2) weeks with delivery of a healthy, 2, 700-gram newborn.
Cervical pregnancy is usually considered a life-threatening event. Other factors such as concomitant intrauterine pregnancy and the patient's infertility history generally would be secondary concerns. In this case, we were able to selectively terminate the cervical pregnancy, while preserving the intrauterine one, allowing this couple to have a healthy newborn. Further cases will be necessary to appropriately define risk rates for such an approach.
寻找一种合适的技术,在维持同时存在的宫内妊娠存活的情况下,选择性地终止宫颈植入的胚胎。
一名34岁患者在4次体外受精尝试后成功怀上双胞胎。超声检查显示宫内和宫颈均有存活妊娠。鉴于我们在氯化钾注射减胎方面的经验,我们让患者尝试减少宫颈妊娠。
在此病例中,经腹扫描获得了最佳的可视化效果。一根6英寸的20号脊椎穿刺针经宫颈插入并 maneuvered 进入胚胎胸腔。甚至在能够注射氯化钾之前胎儿心率就停止了。然后注入3立方厘米生理盐水,以便更好地观察宫颈内的胎儿,并确认心跳停止。患者出现少量阴道出血持续数天。宫内妊娠顺利进展至36(1)/(2)周,分娩出一名健康的2700克新生儿。
宫颈妊娠通常被认为是危及生命的情况。其他因素,如同时存在的宫内妊娠和患者的不孕史,一般会是次要关注点。在此病例中,我们能够选择性地终止宫颈妊娠,同时保留宫内妊娠,使这对夫妇拥有了一个健康的新生儿。需要更多病例来恰当界定这种方法的风险率。