Chopra A
Department of Medicine, University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, Stratford 08084-1504, USA.
J Am Osteopath Assoc. 2000 Jan;100(1 Suppl):S1-4. doi: 10.7556/jaoa.2000.100.1.1s.
Osteoporosis is a major public health problem. It is a skeletal disorder characterized by low bone mass and an increased susceptibility to fractures. In the United States, it affects more than 25 million people, accounts for 1.5 million fractures annually, and costs the nation in excess of $10 billion. The consequences of osteoporosis include decreased functional independence and increased morbidity and mortality. Osteoporosis is a multifactorial disease. The pathogenesis of the disorder has genetic, hormonal, and environmental influences that affect peak bone mass, perimenopausal bone loss, and age-dependent bone loss.
骨质疏松症是一个重大的公共卫生问题。它是一种以骨量低和骨折易感性增加为特征的骨骼疾病。在美国，它影响着超过2500万人，每年导致150万例骨折，给国家造成的损失超过100亿美元。骨质疏松症的后果包括功能独立性下降以及发病率和死亡率增加。骨质疏松症是一种多因素疾病。该疾病的发病机制受到遗传、激素和环境因素的影响，这些因素会影响峰值骨量、围绝经期骨质流失和年龄相关性骨质流失。
