Bluth R, Banaschak H
Acta Biol Med Ger. 1976;35(6):709-13.
When human erythrocytes are incubated in a suspension medium containing noradrenaline, they take up noradrenaline in a reaction proceeding in two phases. In a rapid first reaction noradrenaline is bound by the cells by adsorption at pH-values above 6.0; this reaction follows Freundlich's isotherms. Subsequently, noradrenaline is taken up much more slowly by transmembranous diffusion into the cells. Neither reaction can be influenced by inhibitors such as N-ethyl maleinimide, ouabain, alpha- or beta-receptor blockers.
当人体红细胞在含有去甲肾上腺素的悬浮培养基中孵育时，它们会在一个分两个阶段进行的反应中摄取去甲肾上腺素。在第一个快速反应中，去甲肾上腺素在pH值高于6.0时通过吸附作用与细胞结合；该反应遵循弗罗因德利希等温线。随后，去甲肾上腺素通过跨膜扩散进入细胞的速度要慢得多。这两个反应都不受诸如N - 乙基马来酰亚胺、哇巴因、α或β受体阻滞剂等抑制剂的影响。
