Manianin I I
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.
Biofizika. 1999 Nov-Dec;44(6):1115-8.
The existence of an optimum radius of fibre is shown, when the physical parameters of the intracellular medium and the nonexcitable dendritic membrane are known and the length and load resistance are fixed. This provides the maximum potential for the proximal end of the fibre if synaptic conductance is distributed uniformly along the fibre. A formula for calculating the soma potential of the whole neuron is proposed. The optimal ratio l/lambda is 0.9193 ... if the volume of the fibre and synaptic conductivity are fixed.
当细胞内介质和非兴奋性树突膜的物理参数已知,且纤维长度和负载电阻固定时,可显示出纤维存在最佳半径。如果突触电导沿纤维均匀分布,这将为纤维近端提供最大电位。提出了一种计算整个神经元胞体电位的公式。如果纤维体积和突触电导率固定,最佳的l/λ比值为0.9193…