Pilinskaia M A, Dybskiĭ S S, Red'ko D V
Tsitol Genet. 1999 Nov-Dec;33(6):39-44.
One of the critical human group of potential risk is the group of population from 30-km zone around the Chernobyl nuclear power plant. The cytogenetical examination of 12 persons (8 man, 4 woman, 30-60 years old) from 5 villages situated in north-west and south-east directions from the ChNPP in the frame of this zone was conducted. The data of the conventional analysis showed relatively low cytogenetic effects comparable with the effects in exposed people out of the zone (the mean level of unstable cytogenetic markers in different villages was 0.21-0.35 per 100 cells). The level of stable translocations in one case (woman, 59 years old) determined using FISH (16.62 per 100 cells for the whole genome) exceeded their spontaneous aged frequency and confirmed the high sensitivity of this method for the evaluation of real radiation exposure.
潜在风险的关键人群之一是切尔诺贝利核电站周边30公里区域内的人群。在此区域范围内，对位于切尔诺贝利核电站西北和东南方向5个村庄的12人（8名男性，4名女性，年龄在30至60岁之间）进行了细胞遗传学检查。常规分析数据显示，细胞遗传学效应相对较低，与该区域外受辐射人群的效应相当（不同村庄不稳定细胞遗传学标记的平均水平为每100个细胞0.21 - 0.35个）。使用荧光原位杂交（FISH）确定的1例（59岁女性）稳定易位水平（全基因组每100个细胞16.62个）超过了其自发衰老频率，并证实了该方法在评估实际辐射暴露方面的高敏感性。
