Ogata K, Kawarada Y, Shibata K, Nishio T, Hara N
Department of Pulmonary Disease, Kitakyusyu Municipal Medical Center, Japan.
Nihon Kokyuki Gakkai Zasshi. 1999 Dec;37(12):979-82.
A 67-year-old woman underwent surgery for cancer of both breasts (right: mastectomy, left: conserving surgery), and received 60 Gy radiation to the left postoperative breast. Three months later, cough and fever developed. A chest radiograph demonstrated infiltrative shadows in the left lung field. Transbronchial lung biopsy specimens disclosed organizing exudates in the alveolar spaces and bronchioles. After treatment with prednisolone, the clinical symptoms and radiographic infiltrates disappeared. This was a case of pulmonary radiation injury pathologically manifested by signs of bronchiolitis obliterans with organizing pneumonia.
一名67岁女性接受了双侧乳腺癌手术(右侧:乳房切除术,左侧:保乳手术),术后对左侧乳房进行了60 Gy的放疗。三个月后,出现咳嗽和发热。胸部X线片显示左肺野有浸润性阴影。经支气管肺活检标本显示肺泡腔和细支气管内有组织性渗出物。使用泼尼松龙治疗后,临床症状和影像学上的浸润消失。这是一例肺放射性损伤病例,病理表现为闭塞性细支气管炎伴机化性肺炎的征象。