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哪些患者接受青光眼治疗?一项观察性分析。

Which patients are treated for glaucoma? An observational analysis.

作者信息

Bohn R L, Gurwitz J H, Yeomans S M, Glynn R J, Pasquale L R, Walker A M, Avorn J

机构信息

Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

J Glaucoma. 2000 Feb;9(1):38-44. doi: 10.1097/00061198-200002000-00008.

Abstract

PURPOSE

More than one million patients in the United States are treated for glaucoma, although little is known about the typical clinical characteristics of this group of patients and the type of therapy they receive. This study was conducted to describe the demographic and diagnostic characteristics of patients beginning long-term drug therapy for glaucoma.

METHODS

This cross-sectional study included 544 patients beginning topical glaucoma medication regimens who received care at a group model health-maintenance organization (HMO) located in central Massachusetts. The primary medical records of 544 patients beginning topical glaucoma medication between 1987 and 1990 were reviewed to ascertain the presence of three clinical findings: intraocular pressure (IOP) > or = 22 mmHg; optic disc changes including cup-to-disc ratio > or = 0.8, cup-to-disc asymmetry > or = 0.2, or morphologic disc changes consistent with glaucomatous optic neuropathy; and visual field defect consistent with glaucoma.

RESULTS

A majority of the 544 patients (86%) were diagnosed as having primary open-angle glaucoma (POAG) by their physicians. Almost half (44.7%) of these patients had only an elevation in IOP without other clinical findings, and 9% met none of the above criteria for glaucoma according to information in the medical record.

CONCLUSION

In this setting, most patients who were prescribed drug therapy for POAG were treated for an elevation in IOP alone in the absence of other ophthalmologic characteristics of glaucoma.

摘要

目的

在美国,有超过100万患者接受青光眼治疗,但对于这群患者的典型临床特征以及他们所接受的治疗类型却知之甚少。本研究旨在描述开始接受青光眼长期药物治疗的患者的人口统计学和诊断特征。

方法

这项横断面研究纳入了544名开始接受局部青光眼药物治疗方案的患者,这些患者在位于马萨诸塞州中部的一个团体模式健康维护组织(HMO)接受治疗。回顾了1987年至1990年间开始接受局部青光眼药物治疗的544名患者的主要医疗记录,以确定是否存在以下三项临床发现:眼压(IOP)≥22 mmHg;视盘改变,包括杯盘比≥0.8、杯盘不对称≥0.2或与青光眼性视神经病变一致的视盘形态改变;以及与青光眼一致的视野缺损。

结果

544名患者中的大多数(86%)被医生诊断为原发性开角型青光眼(POAG)。这些患者中近一半(44.7%)仅眼压升高而无其他临床发现,根据病历信息,9%的患者不符合上述任何青光眼标准。

结论

在这种情况下,大多数被开了POAG药物治疗的患者仅因眼压升高而接受治疗,而没有青光眼的其他眼科特征。

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