Yeo P B, Gwee H M, Tan N B, Ho C L, Cheah J S, Lee G S, Lim P, Jacob E, Tan Y T, Tambyah J A, Tan B Y
Aust N Z J Med. 1976 Aug;6(4):311-4. doi: 10.1111/imj.1976.6.4.311.
Baseline thyroid function tests (including total serum thyroxine iodide-T4I, total serum tri-iodothyronine T3 as well as T3 Sephadex Uptake Studies (T3U)) were determined in 82 normal Asian subjects. In addition, another group of normal volunteers (39) were assessed as regard serum and 24-hour urinary iodide levels to gauge the iodide status of the community; the results were comparable to that of goitre-free regions of the world. Having established the range of values of normal thyroid function tests, 103 consecutive clinically thyrotoxic patients (both new and relapsed cases) were similarly studied in an attempt to elucidate the magnitude of the problem of T3 toxicosis, and its relation to the iodide status in Singapore. Only three clinically hyperthyroid patients were foudn to have normal PBI T3 levels. A detailed analysis and discussion of the data is presented. It is concluded that T3 toxicosis is a rarity in Singapore.
对82名正常亚洲受试者进行了基础甲状腺功能测试（包括血清总甲状腺素碘 - T4I、血清总三碘甲状腺原氨酸T3以及T3葡聚糖凝胶摄取研究（T3U））。此外，对另一组正常志愿者（39名）进行了血清和24小时尿碘水平评估，以衡量该社区的碘状况；结果与世界上无甲状腺肿地区的结果相当。在确定了正常甲状腺功能测试的数值范围后，对103例连续的临床甲状腺毒症患者（包括新发病例和复发患者）进行了类似研究，试图阐明T3中毒问题的严重程度及其与新加坡碘状况的关系。仅发现3例临床甲状腺功能亢进患者的PBI T3水平正常。本文对数据进行了详细分析和讨论。得出的结论是，T3中毒在新加坡很少见。
