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免疫功能低下患者的非创伤性鼻中隔脓肿:病因、识别、治疗及后遗症

Nontraumatic nasal septal abscesses in the immunocompromised: etiology, recognition, treatment, and sequelae.

作者信息

Shah S B, Murr A H, Lee K C

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco 94143, USA.

出版信息

Am J Rhinol. 2000 Jan-Feb;14(1):39-43. doi: 10.2500/105065800781602975.

DOI:10.2500/105065800781602975
PMID:10711331
Abstract

Proper management of a nasal septal abscess requires prompt diagnosis, adequate surgical drainage, and antibiotics to prevent the potentially dangerous spread of infection and the development of severe functional and cosmetic sequelae. Most septal abscesses are the result of trauma to the nose with septal hematoma and subsequent infection. We present our experience with nasal septal abscesses in five immunocompromised patients without history of nasal trauma. All patients were treated with surgical drainage and antibiotics. The infections in four patients resolved, whereas in the fifth, the infection led to death. We report these cases to depict alternate etiologies of nasal septal abscess, particularly in the immunocompromised patient. Our review illustrates the wide spectrum of disease presentation, provides treatment strategies, and emphasizes the potentially catastrophic sequelae of this disease when unrecognized. With the growing number of immunocompromised individuals, it is important to recognize the potential for immunocompromise to influence the development of septal abscess.

摘要

鼻中隔脓肿的妥善处理需要及时诊断、充分的手术引流以及使用抗生素,以防止感染的潜在危险扩散以及严重功能和美容后遗症的发生。大多数鼻中隔脓肿是鼻部外伤导致鼻中隔血肿并继发感染的结果。我们介绍了5例无鼻外伤史的免疫功能低下患者鼻中隔脓肿的治疗经验。所有患者均接受了手术引流和抗生素治疗。4例患者的感染得到解决,而第5例患者的感染导致死亡。我们报告这些病例以描述鼻中隔脓肿的其他病因,特别是在免疫功能低下的患者中。我们的综述阐述了疾病表现的广泛范围,提供了治疗策略,并强调了这种疾病未被识别时可能产生的灾难性后果。随着免疫功能低下个体数量的增加,认识到免疫功能低下对鼻中隔脓肿形成的潜在影响非常重要。

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