Campos A, Vaz C P, Campilho F, Morais A, Guimarães M A, Lopes C, Portal A, Carvalhais A, Pimentel P
Bone Marrow Transplant Unit, Instituto Português de Oncologia, Porto, Portugal.
Bone Marrow Transplant. 2000 Mar;25(5):567-9. doi: 10.1038/sj.bmt.1702163.
Tuberculosis is an uncommon infectious complication after stem cell transplantation. We report a patient who presented with a brain mass, 3 months after pulmonary tuberculosis had been diagnosed and while he was receiving triple antituberculous therapy. He had extensive chronic GVHD. The diagnosis was made after biopsy of the lesion. The cerebral mass was excised, antituberculous treatment was maintained and the patient made a complete neurologic recovery. Six months later, he died of gram-negative septic shock. Mycobacterial infections should be considered in allograft recipients with chronic GVHD and solid lesions in the brain. Bone Marrow Transplantation (2000) 25, 567-569.
肺结核是干细胞移植后一种罕见的感染性并发症。我们报告一例患者，在诊断为肺结核3个月后且正在接受三联抗结核治疗时出现脑部肿块。他患有广泛的慢性移植物抗宿主病（GVHD）。通过病变活检后做出诊断。切除了脑部肿块，继续进行抗结核治疗，患者神经系统完全恢复。6个月后，他死于革兰氏阴性菌败血症休克。对于患有慢性GVHD且脑部有实体病变的同种异体移植受者，应考虑分枝杆菌感染。《骨髓移植》（2000年）第25卷，第567 - 569页
