Terao T, Iwata N, Kanazawa K, Takano T, Takahashi N, Hayashi T, Sugawara Y
Department of Psychiatry, University of Occupational and Environmental Health, Japan.
Acta Psychiatr Scand. 2000 Mar;101(3):231-4.
The purpose of the present study was to investigate an association between serum cholesterol levels and depressive state.
Physical examinations and mental assessments were performed for 13702 human dock visitors. We obtained 13571 sets of complete data for serum total cholesterol, the scores for depressive state and possible confounders such as sex, age, body weight, body mass index (BMI), recent weight loss, total protein and concomitant medical diagnoses.
Their depressive state varied significantly across the serum cholesterol levels after adjusting age and gender. After controlling all the above confounding variables the significance still remained, not only in the categorical analysis but also in the continuous analysis.
The present findings suggest that there is an association between cholesterol and depressive state.
本研究旨在调查血清胆固醇水平与抑郁状态之间的关联。
对13702名到人体码头参观的人员进行了体格检查和心理评估。我们获得了13571组关于血清总胆固醇、抑郁状态评分以及可能的混杂因素（如性别、年龄、体重、体重指数（BMI）、近期体重减轻、总蛋白和伴随的医学诊断）的完整数据。
在调整年龄和性别后，他们的抑郁状态在不同血清胆固醇水平之间存在显著差异。在控制了所有上述混杂变量后，这种显著性仍然存在，不仅在分类分析中如此，在连续分析中也是如此。
目前的研究结果表明胆固醇与抑郁状态之间存在关联。
