Ohshige K, Morio S, Mizushima S, Kitamura K, Tajima K, Ito A, Suyama A, Usuku S, Saphonn V, Heng S, Hor L B, Tia P, Soda K
Department of Public Health, Yokohama City University, School of Medicine, Japan.
Epidemiol Infect. 2000 Feb;124(1):143-52. doi: 10.1017/s0950268899003428.
To describe epidemiological features on HIV prevalence among female commercial sex workers (CSWs), a cross-sectional study on sexual behaviour and serological prevalence was carried out in Cambodia. The CSWs were interviewed on their demographic characters and behaviour and their blood samples were taken for testing on sexually transmitted diseases, including HIV, Chlamydia trachomatis, syphilis, and hepatitis B. Associations between risk factors and HIV seropositivity were analysed. High seroprevalence of HIV and Chlamydia trachomatis IgG antibody (CT-IgG-Ab) was shown among the CSWs (54 and 81.7%, respectively). Univariate logistic regression analyses showed an association between HIV seropositivity and age, duration of prostitution, the number of clients per day and CT-IgG-Ab. Especially, high-titre chlamydial seropositivity showed a strong significant association with HIV prevalence. In multiple logistic regression analyses, CT-IgG-Ab with higher titre was significantly independently related to HIV infection. These suggest that existence of Chlamydia trachomatis is highly related to HIV prevalence.
为描述女性商业性工作者(CSW)中艾滋病毒流行情况的流行病学特征,在柬埔寨开展了一项关于性行为和血清学流行率的横断面研究。对CSW进行了人口统计学特征和行为方面的访谈,并采集她们的血样以检测包括艾滋病毒、沙眼衣原体、梅毒和乙型肝炎在内的性传播疾病。分析了危险因素与艾滋病毒血清阳性之间的关联。CSW中艾滋病毒和沙眼衣原体IgG抗体(CT-IgG-Ab)的血清流行率较高(分别为54%和81.7%)。单因素逻辑回归分析显示,艾滋病毒血清阳性与年龄、卖淫持续时间、每日客户数量以及CT-IgG-Ab之间存在关联。特别是,高滴度衣原体血清阳性与艾滋病毒流行率呈现出强烈的显著关联。在多因素逻辑回归分析中,较高滴度的CT-IgG-Ab与艾滋病毒感染显著独立相关。这些结果表明,沙眼衣原体的存在与艾滋病毒流行率高度相关。