Yamashiro C, Ohnishi Y, Kanenishi K, Hayashi K, Yanagihara T, Hata T
Department of Perinatology, Kagawa Medical University, Miki, Kagawa, Japan.
Gynecol Obstet Invest. 2000;49(3):156-9. doi: 10.1159/000010238.
The objective of the present study was to evaluate whether maternal and fetal circulating angiogenin levels in pregnancies with small-for-gestational- age (SGA) infants are different from those in pregnancies with appropriate-for-gestational-age (AGA) infants.
Maternal and fetal circulating angiogenin concentrations were compared at birth between 16 pregnancies with SGA (7 delivered vaginally and 9 delivered by elective cesarean section) and 46 pregnancies with AGA (27 delivered vaginally and 19 delivered by cesarean section). Serum angiogenin level was measured with an enzyme-linked immunosorbent assay.
There were no significant differences in maternal and fetal serum angiogenin levels between the two groups. However, maternal serum angiogenin levels were significantly higher than those in fetal serum within both SGA and AGA infant pregnancies. There were no significant differences in maternal and fetal serum angiogenin levels between vaginal and cesarean delivered pregnancies in both SGA and AGA groups.
These results suggest that there is no difference in angiogenin synthesis between SGA and AGA pregnancies.
本研究的目的是评估小于胎龄（SGA）儿妊娠中母体和胎儿循环血管生成素水平是否与适于胎龄（AGA）儿妊娠中的水平不同。
比较了16例SGA妊娠（7例经阴道分娩，9例择期剖宫产）和46例AGA妊娠（27例经阴道分娩，19例剖宫产）出生时母体和胎儿循环血管生成素的浓度。采用酶联免疫吸附测定法测量血清血管生成素水平。
两组间母体和胎儿血清血管生成素水平无显著差异。然而，在SGA和AGA儿妊娠中，母体血清血管生成素水平均显著高于胎儿血清中的水平。SGA组和AGA组中，经阴道分娩和剖宫产的妊娠之间母体和胎儿血清血管生成素水平均无显著差异。
这些结果表明，SGA妊娠和AGA妊娠之间血管生成素合成没有差异。
