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自体动脉移植物覆盖支架植入人体冠状动脉:一种新技术。

Implantation of stents covered by autologous arterial grafts in human coronary arteries: a new technique.

作者信息

Stefanadis C, Toutouzas K, Tsiamis E, Kallikazaros I, Stratos C, Vlachopoulos C, Vavuranakis M, Toutouzas P

机构信息

9 Tepeleniou Str., Paleo Psychico, Athens, 15452, Greece.

出版信息

J Invasive Cardiol. 2000 Jan;12(1):7-12.

Abstract

UNLABELLED

A renewed interest in radial artery conduits for bypass surgery has emerged during the last few years. In order to combine a surgical with a percutaneous technique, stents were covered by radial arterial grafts. The purpose of this study was to evaluate the feasibility of, and the immediate and long-term results after, intracoronary implantation of stents covered by autologous arterial grafts.

METHODS

A graft was removed from the radial artery. A conventional stent was then covered by the arterial graft. The autologous arterial graft was stabilized on the stent by sutures. Fifteen covered stents were implanted in 15 patients (56.1 +/- 17.3 years old) in all coronary vessels.

RESULTS

The procedure of stent covering was feasible and short in duration. Procedural success was 100% with no in-hospital stent thrombosis, Q-wave myocardial infarction or death. In 14 patients (93.3%), including the patients with clinical restenosis, a repeat angiography was performed (minimum lumen diameter immediately after procedure: 3.01 +/- 0.22 mm, at follow-up: 2.56 +/- 0.90 mm). Target lesion revascularization was required in 2 patients. The event-free survival rate at 2 years was 87%.

CONCLUSION

Intracoronary implantation of stents covered by an autologous arterial graft may be performed safely with excellent long-term results. A multicenter study is required to assess the efficacy.

摘要

未标注

在过去几年中,人们对用于搭桥手术的桡动脉血管再次产生了兴趣。为了将外科手术与经皮技术相结合,用桡动脉移植物覆盖支架。本研究的目的是评估自体动脉移植物覆盖支架冠状动脉内植入的可行性以及即刻和长期结果。

方法

从桡动脉取下一段移植物。然后用动脉移植物覆盖一个传统支架。通过缝线将自体动脉移植物固定在支架上。在15例患者(年龄56.1±17.3岁)的所有冠状动脉血管中植入了15个带膜支架。

结果

支架覆盖操作可行且持续时间短。手术成功率为100%,无院内支架血栓形成、Q波心肌梗死或死亡。14例患者(93.3%),包括临床再狭窄患者,进行了再次血管造影(术后即刻最小管腔直径:3.01±0.22mm,随访时:2.56±0.90mm)。2例患者需要进行靶病变血运重建。2年时无事件生存率为87%。

结论

自体动脉移植物覆盖支架冠状动脉内植入可安全进行,长期效果良好。需要进行多中心研究来评估其疗效。

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