Sela J, Ulmansky M, Sela M, Yaffe A, Soskolne A
Pharmacol Ther Dent. 1975;2(3-4):245-52.
The effect of solutions of lidocaine, with and without adrenaline, on the blood vessels of the dental pulp and periodontal ligament in rat molars was examined. The vessels were visualized by intravascular injection of a supension of carbon particles. The results indicate that the anesthetic solution alone does have a local effect on the blood vessels. Local anesthetic solutions containing adrenaline had a more marked effect; in addition, a dose-dependent systemic effect of adrenaline was noted.
研究了含和不含肾上腺素的利多卡因溶液对大鼠磨牙牙髓和牙周膜血管的影响。通过血管内注射碳颗粒悬浮液使血管可视化。结果表明，单纯麻醉溶液确实对血管有局部作用。含肾上腺素的局部麻醉溶液作用更显著；此外，还观察到肾上腺素的剂量依赖性全身作用。
