Gadomski A, Jaranowska D, Ebinger K, Ozimek W, Brzewski M
Katedry i Kliniki Pediatrii, Hematologii i Onkologii Akademii Medycznej w Warszawie.
Wiad Lek. 1998;51 Suppl 4:266-9.
The atrial catheter (subcutaneous port) was used in a 5 year old boy with Hodgkin's disease for the administration of antineoplastic agents and other drugs. Catheter was flushed daily or every 2 weeks with heparin solution (5 U/ml)). The complications including infection and occlusion were not observed in this patient during observation time. Routine echocardiography performed after eight months of usage of the catheter showed right atrial thrombus. Because of the failure of 14 days fibrinolytic therapy (Actylise) surgical thrombectomy was performed. Bacteriological culture of the surgical specimen was positive for Pseudomonas aeruginosa. The post-operative period passed without complications. Follow-up echocardiography findings were normal. The probable reason of thrombus formation could be damage of the right atrium by stream of drugs or balloting ending of the catheter.
一名5岁患有霍奇金病的男孩使用心房导管（皮下端口）来输注抗肿瘤药物和其他药物。导管每天或每2周用肝素溶液（5 U/ml）冲洗。在观察期内，该患者未观察到包括感染和堵塞在内的并发症。导管使用8个月后进行的常规超声心动图检查显示右心房血栓形成。由于14天的纤溶治疗（阿替普酶）失败，遂进行了手术取栓。手术标本的细菌培养显示铜绿假单胞菌呈阳性。术后过程无并发症。随访超声心动图检查结果正常。血栓形成的可能原因可能是药物流对右心房的损伤或导管的摆动末端。
