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Heterologous expression and assays for photoreceptor guanylyl cyclases and guanylyl cyclase activating proteins.

作者信息

Hurley J B, Dizhoor A M

机构信息

Department of Biochemistry, Howard Hughes Medical Institute, University of Washington, Seattle 98195, USA.

出版信息

Methods Enzymol. 2000;315:708-17. doi: 10.1016/s0076-6879(00)15876-8.

DOI:10.1016/s0076-6879(00)15876-8
PMID:10736735
Abstract
摘要

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Constitutive excitation by Gly90Asp rhodopsin rescues rods from degeneration caused by elevated production of cGMP in the dark.
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