Jelski W, Chrostek L, Szmitkowski M
Diagnostyki Biochemicznej Akademii Medycznej w Białymstoku.
Postepy Hig Med Dosw. 1999;53(6):871-83.
More than 90% of ingested ethanol is metabolized in the body to acetaldehyde and acetate. Ethanol is metabolized in the liver via three distinct enzymatic pathways: alcohol dehydrogenase (ADH), the microsomal ethanol oxidizing system (MEOS) and catalase. It is generally accepted that alcohol dehydrogenase is the predominant pathway for hepatic ethanol oxidation. Acetaldehyde is metabolized to acetate by a group of dehydrogenase enzymes called aldehyde dehydrogenase.
摄入的乙醇90%以上在体内代谢为乙醛和乙酸盐。乙醇在肝脏中通过三种不同的酶促途径进行代谢:乙醇脱氢酶(ADH)、微粒体乙醇氧化系统(MEOS)和过氧化氢酶。人们普遍认为乙醇脱氢酶是肝脏乙醇氧化的主要途径。乙醛通过一组称为乙醛脱氢酶的脱氢酶代谢为乙酸盐。