Grubitzsch H, Beholz S, Wollert H G, Eckel L
Clinic for Cardiothoracic and Vascular Surgery, Heart and Diabetes Centre Mecklenburg-Vorpommern, Klinikum Karlsburg, Germany.
Cardiovasc Pathol. 2000 Jan-Feb;9(1):53-4. doi: 10.1016/s1054-8807(99)00036-8.
Werner syndrome is a rare autosomal recessive disorder characterized by the appearance of premature aging. We report on severe aortic and mitral valve calcification in an 18-year-old girl, necessitating double valve replacement. These special cardiovascular findings are discussed with regard to diagnosis and treatment.
沃纳综合征是一种罕见的常染色体隐性疾病,其特征为过早衰老。我们报告了一名18岁女孩出现严重的主动脉瓣和二尖瓣钙化,需要进行双瓣膜置换。本文就这些特殊的心血管表现进行了诊断和治疗方面的讨论。