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[食管浸润性颗粒细胞瘤:两例病例描述]

[Infiltrating granular cell tumor of the esophagus: a description of two cases].

作者信息

Chatelain D, Terris B, Molas G, Belghiti J, Degott C, Fléjou J

机构信息

Service d'Anatomie pathologique, Hôpital Beaujon, Clichy, France.

出版信息

Ann Pathol. 2000 Mar;20(2):158-62.

Abstract

Granular cell tumor of the esophagus is an unusual tumor. It presents usually as a small and well limited lesion, localized in the mucosa or the submucosa. We report two cases of granular cell tumor of the esophagus, remarkable for their infiltrative growth. The tumor invaded the esophageal muscularis propria in one case and went through the adventitia in the other. There was no recurrence 1 year and 7 years after surgery, despite an incomplete resection in the second case. Thirteen cases of infiltrative granular cell tumors of the esophagus have been published. They are usually responsible for dysphagia. They can invade the muscularis propria and the adventitia as well as the periesophageal organs. There is no recurrence, even after an incomplete resection. The infiltrative feature of the granular cell tumors of the esophagus, by itself, cannot be considered as a malignant feature. The diagnosis of malignant granular cell tumor of the esophagus lies on the discover of metastases.

摘要

食管颗粒细胞瘤是一种罕见的肿瘤。它通常表现为一个小的、边界清晰的病变,位于黏膜或黏膜下层。我们报告两例食管颗粒细胞瘤,其显著特点是浸润性生长。其中一例肿瘤侵犯了食管固有肌层,另一例穿过了外膜。尽管第二例手术切除不完全,但术后1年和7年均无复发。已发表了13例食管浸润性颗粒细胞瘤。它们通常导致吞咽困难。它们可侵犯固有肌层、外膜以及食管周围器官。即使切除不完全也不会复发。食管颗粒细胞瘤的浸润性特征本身不能被视为恶性特征。食管恶性颗粒细胞瘤的诊断在于发现转移灶。

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