Szigeti N, Horváth O P, Kassai G, Gömöri E, Fábián G
Pécsi Tudományegyetem, Altalános Orvostudományi Kar, II. Belgyógyászati Klinika és Nefrológiai Centrum.
Orv Hetil. 2001 Apr 8;142(14):733-5.
Granular cell tumor is a relatively rare, mostly benign lesion, that can be found in almost every organ, however, only 2% of the cases is oesophageal. It is named after the eosinophilic S-100 protein positive granula in the cytoplasm of the tumor cells. Since patients with oesophageal granular cell tumor are mostly symptomless, the tumor is usually found accidentally. Even in patients with dysphagia, contrast radiograph and gastroscopy show an atypical picture, therefore, the diagnosis is based on the histological examination. Therapy is usually conservative, but surgical treatment might be necessary sometimes. A patient with severe dysphagia is reported here. She was diagnosed with a granular cell tumor in the oesophagus, and the tumor was surgically removed.
颗粒细胞瘤是一种相对罕见的、大多为良性的病变,几乎可在每个器官中发现,然而,仅有2%的病例发生于食管。它因肿瘤细胞胞质中嗜酸性S-100蛋白阳性颗粒而得名。由于食管颗粒细胞瘤患者大多无症状,肿瘤通常是偶然发现的。即使是有吞咽困难的患者,造影检查和胃镜检查也显示出非典型表现,因此,诊断基于组织学检查。治疗通常是保守的,但有时可能需要手术治疗。本文报道了一名有严重吞咽困难的患者。她被诊断为食管颗粒细胞瘤,并接受了手术切除肿瘤。