Occhionorelli S, Carella M, Presicce L, Pellegrini D, Pennella A, Piscitelli D, Pollinzi Fonte V
Dipartimento di Metodologia Clinica e Tecnologie Medico-Chirurgiche, Università degli Studi di Bari.
Chir Ital. 1999 Nov-Dec;51(6):489-96.
The layout of the work has stayed motivated from the recent observation of mixed carcinoid, located to the appendix and wide to the peritoneal cable, joint to our observation in an elderly patient with aspecific demonstration clinical-symptomatologic. The study of the endocrine tumors is in continuous evolution also if, to the actual state, there is a better comprehension of this neoplasm, variegated and complex and, under some appearances, still not known well. Jejunoileal carcinoid tumors differ, under many appearances, from those occurring in other sites of the gut. They have relatively high rate of transmural invasion and aggressive clinical behavior, contrasted by a scarce objectivity; the demonstration of symptoms generally implicates the presence of an illness in advanced stage. Also pharmacological therapy made important progress, with the possibility of administer composed able to interfere with the development and the neoplastic growth.
该研究的布局受到最近一项观察结果的启发，该观察涉及位于阑尾且广泛累及腹膜索带的混合性类癌，这与我们在一位临床表现不典型的老年患者中的观察结果相符。内分泌肿瘤的研究一直在不断发展，尽管就目前的情况而言，对这种多样、复杂且在某些方面仍未被充分了解的肿瘤有了更好的认识。空肠回肠类癌肿瘤在许多方面与发生在肠道其他部位的类癌不同。它们具有相对较高的透壁侵犯率和侵袭性临床行为，但其客观性不足；症状的表现通常意味着疾病已处于晚期。药物治疗也取得了重要进展，现在有可能使用能够干扰肿瘤发生和生长的药物组合。
