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[恶性淋巴瘤中脾脏局灶性回声增强:一个诊断难题]

[Focal echogenic splenic involvement in malignant lymphoma: a diagnostic problem].

作者信息

Riera-Knorrenschild J, Görg C, Dennhardt N, Restrepo I, Neubauer A

机构信息

Medizinische Universitätsklinik, Marburg.

出版信息

Ultraschall Med. 2000 Feb;21(1):3-7. doi: 10.1055/s-2000-8642.

DOI:10.1055/s-2000-8642
PMID:10746277
Abstract

AIM

The aim of our study was to describe clinical data, frequency of the findings, sonographic patterns, confirmation of diagnosis, and differential diagnosis of focal echorich splenic lymphoma involvement.

PATIENTS

During the last 20 years a focal splenic lesion was found in 178 patients with malignant lymphoma. Echorich splenic lesions were seen in 11 out of 178 cases (6.2%).

METHODS

Splenic size, echomorphology of lesions, size and number of lesions, and presentation during sonographic follow-up examination were presented.

RESULTS

Echorich infiltrates of the spleen were predominantly seen in patients with low grade Non-Hodgkin-Lymphoma (9 out of 11), the size of lesions mostly was less than 3 cm in diameter (9 out of 11), the underlying splenic size was over 8 x 20 cm in 9 out of 11 patients. Diagnosis was confirmed by sonographic follow-up (n = 11) and autopsy (n = 1).

CONCLUSION

Echorich splenic lymphoma involvement is a rare event and is characterised by a variable presentation during follow-up. Up to date the clinic significance of our observation is still unclear.

摘要

目的

我们研究的目的是描述局灶性脾淋巴瘤累及的临床数据、发现频率、超声图像模式、诊断确认及鉴别诊断。

患者

在过去20年中,178例恶性淋巴瘤患者发现有局灶性脾病变。178例中有11例(6.2%)出现脾回声增强性病变。

方法

呈现脾脏大小、病变的回声形态、病变大小及数量,以及超声随访检查中的表现。

结果

脾回声增强性浸润主要见于低度非霍奇金淋巴瘤患者(11例中的9例),病变大小大多直径小于3厘米(11例中的9例),11例中有9例患者的脾脏大小超过8×20厘米。通过超声随访(n = 11)和尸检(n = 1)确诊。

结论

脾回声增强性淋巴瘤累及是一种罕见情况,其特征是随访期间表现多样。目前我们观察结果的临床意义仍不明确。

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1
[Focal echogenic splenic involvement in malignant lymphoma: a diagnostic problem].[恶性淋巴瘤中脾脏局灶性回声增强:一个诊断难题]
Ultraschall Med. 2000 Feb;21(1):3-7. doi: 10.1055/s-2000-8642.
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[Ultrasound involvement of the spleen in non-Hodgkin's lymphomas].[非霍奇金淋巴瘤脾脏的超声表现]
Ultraschall Med. 1995 Jun;16(3):104-8. doi: 10.1055/s-2007-1003164.
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Malignant splenic lymphoma: sonographic patterns, diagnosis and follow-up.恶性脾脏淋巴瘤:超声表现、诊断及随访
Clin Radiol. 1997 Jul;52(7):535-40. doi: 10.1016/s0009-9260(97)80331-5.
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Sonographic patterns of the affected spleen in malignant lymphoma.
J Clin Ultrasound. 1990 Sep;18(7):569-74. doi: 10.1002/jcu.1870180708.
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[Frequency, pattern and differential diagnosis of echogenic splenic changes: sonographic follow-up study].
Ultraschall Med. 2000 Aug;21(4):151-9. doi: 10.1055/s-2000-6925.
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Splenic lesions: sonographic patterns, follow-up, differential diagnosis.
Eur J Radiol. 1991 Jul-Aug;13(1):59-66. doi: 10.1016/0720-048x(91)90058-4.
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[Differential echogenic focal splenic lesion diagnosis].[脾脏局灶性回声差异病变的诊断]
Praxis (Bern 1994). 2003 May 28;92(22):1037-42. doi: 10.1024/0369-8394.92.22.1037.
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Ultrasound diagnosis of splenic lymphoma: ROC analysis of multidimensional splenic indices.脾脏淋巴瘤的超声诊断:多维脾脏指数的受试者工作特征分析
Br J Radiol. 1993 Oct;66(790):859-64. doi: 10.1259/0007-1285-66-790-859.
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[Sonography in the diagnosis of lesions of abdominal lymph nodes, liver and spleen in malignant lymphoma].
Vopr Onkol. 1997;43(2):198-201.
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Sonography of focal lesions of the spleen.脾脏局灶性病变的超声检查
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