Castro F P, Barrack R L
Tulane University School of Medicine, Department of Orthopaedic Surgery, New Orleans, Louisiana, USA.
Am J Orthop (Belle Mead NJ). 2000 Mar;29(3):187-94.
Core decompression for avascular necrosis (AVN) of the femoral head continues to be a controversial procedure. Meta-analysis techniques were employed to identify 22 studies with a single surgical core decompression technique. A similar procedure identified eight studies that treated patients conservatively. The success rates for core decompression were 84%, 63%, and 29% for Steinberg stages I, II, and III, respectively. Conservatively treated patients with stage 0, I, III, and III AVN demonstrated success rates of 86%, 61%, 59%, and 25%, respectively. Chi-square analysis showed the success rate of core decompression to be statistically higher than conservative treatment for stage I hips only. Large multicenter prospective double-blinded studies with patients randomized to either core decompression or conservative treatment, then stratified by stage, cause, and bilaterality, are needed to determine the best treatment for early-stage AVN.
股骨头缺血性坏死(AVN)的髓芯减压术仍然是一种存在争议的手术。采用荟萃分析技术,确定了22项采用单一手术髓芯减压技术的研究。通过类似程序确定了8项对患者进行保守治疗的研究。对于Steinberg I期、II期和III期,髓芯减压的成功率分别为84%、63%和29%。0期、I期、II期和III期AVN的保守治疗患者的成功率分别为86%、61%、59%和25%。卡方分析表明,仅对于I期髋关节,髓芯减压的成功率在统计学上高于保守治疗。需要开展大型多中心前瞻性双盲研究,将患者随机分为髓芯减压组或保守治疗组,然后按分期、病因和双侧性进行分层,以确定早期AVN的最佳治疗方法。