Becelli R, Frati R, Renzi G, Iannetti G
Division of Maxillo-Facial Surgery, University La Sapienza, Rome, Italy.
J Exp Clin Cancer Res. 1999 Dec;18(4):469-73.
The purpose of this study is to show the connection among tumor histology, surgical treatments and facial nerve postoperative functionality. A retrospective review was conducted on 69 patients with benign and malignant parotid tumors: they underwent surgical treatment for benign and malignant parotid tumors at the Maxillofacial Division of Rome University "La Sapienza" from 1988 to 1997. In our series of patients, we performed conservative superficial parotidectomy, conservative total parotidectomy and radical parotidectomy. Tumor enucleation was reserved for those neoplasms with a limited and restricted mass. The surgical approach was based on mass extension and on histopathologic features. Our findings showed that a careful and a timely diagnosis is very important in order to select a conservative surgical treatment for benign and intermediate grade of malignancy tumors with limited dimensions. Most aggressive histological types, and large mass dimensions require a radical treatment with consequent facial nerve postoperative dysfunctions. Our experience demonstrates that this surgical approach provides a very high rate of success in the cure of tumors and a low rate of facial nerve postoperative dysfunctions.
本研究的目的是揭示肿瘤组织学、手术治疗与面神经术后功能之间的联系。对69例腮腺良恶性肿瘤患者进行了回顾性研究:1988年至1997年期间,他们在罗马大学“La Sapienza”颌面外科接受了腮腺良恶性肿瘤的手术治疗。在我们的患者系列中,我们实施了保守性浅叶腮腺切除术、保守性全腮腺切除术和根治性腮腺切除术。肿瘤剜除术仅适用于那些肿块局限且范围有限的肿瘤。手术方式基于肿块的范围和组织病理学特征。我们的研究结果表明,为了选择对尺寸有限的良性和中度恶性肿瘤进行保守性手术治疗,仔细且及时的诊断非常重要。大多数侵袭性组织学类型以及较大的肿块尺寸需要进行根治性治疗,随之而来的是面神经术后功能障碍。我们的经验表明,这种手术方式在肿瘤治疗中具有很高的成功率,且面神经术后功能障碍发生率较低。