Zhang J, Zhang J G, Song T L, Zhen L, Zhang Y, Zhang K H, Yang Z H, Yu G Y
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Hai Dian District, Beijing, PR China.
Int J Oral Maxillofac Surg. 2008 Jun;37(6):515-20. doi: 10.1016/j.ijom.2008.04.013.
The surgical treatment of malignant parotid gland tumors combined with (125)I seed implant brachytherapy and preservation of the facial nerve is described. Tumor and parotid gland resection with preservation of the facial nerve was carried out in 12 patients with malignant parotid gland tumors. (125)I seeds were implanted into the target area intra- or postoperatively. The extent of regional control of the tumor was followed up, and facial nerve function was evaluated. None of the patients had tumor recurrence during the follow-up period of 50-74 months (median follow-up period, 66 months). Facial nerve function had recovered to normal by 6 months postoperatively in all patients. A limited surgical resection combined with (125)I seed implant brachytherapy is therefore considered to be an alternative treatment for local control of malignant parotid gland tumors with preservation of the facial nerve.
本文描述了腮腺恶性肿瘤的手术治疗联合¹²⁵I粒子植入近距离放疗及面神经保留的情况。对12例腮腺恶性肿瘤患者实施了保留面神经的肿瘤及腮腺切除术。¹²⁵I粒子在术中或术后植入靶区。随访肿瘤区域控制情况，并评估面神经功能。在50 - 74个月的随访期（中位随访期66个月）内，所有患者均未出现肿瘤复发。所有患者术后6个月面神经功能均恢复正常。因此，有限的手术切除联合¹²⁵I粒子植入近距离放疗被认为是一种在保留面神经的情况下局部控制腮腺恶性肿瘤的替代治疗方法。
