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喉癌的亚部位分布与吸烟习惯有关吗?

Is the subsite distribution of laryngeal cancer related to smoking habits?

作者信息

Virtaniemi J A, Hirvikoski P P, Kumpulainen E J, Johansson R T, Pukkala E, Kosma V M

机构信息

Department of Otorhinolaryngology, University of Kuopio and Kuopio University Hospital, Finland.

出版信息

Acta Oncol. 2000;39(1):77-9. doi: 10.1080/028418600431012.

DOI:10.1080/028418600431012
PMID:10752658
Abstract

In Finland traditionally as many as two-thirds of laryngeal cancers have been considered to be supraglottic, while in other countries the majority are glottic. The Finnish observation is based on clinical series diagnosed and treated mainly before the 1960s. The aim of our study was to evaluate the present situation. This study consisted of 279 patients treated in Eastern Finland between 1975 and 1994 and included 145 (52%) glottic, 124 (44%) supraglottic and 10 (4%) subglottic tumours in 260 (93%) men and 19 (7%) women. During this study period, the proportion of glottic tumours remained stable in men but increased in women. The change in smoking habits seems to be the most important reason for the shift from supraglottic to glottic tumours.

摘要

在芬兰,传统上多达三分之二的喉癌被认为是声门上型,而在其他国家,大多数是声门型。芬兰的这一观察结果基于主要在20世纪60年代以前诊断和治疗的临床系列病例。我们研究的目的是评估当前的情况。这项研究包括1975年至1994年在芬兰东部接受治疗的279例患者,其中有145例(52%)为声门型肿瘤,124例(44%)为声门上型肿瘤,10例(4%)为声门下型肿瘤;患者中有260例(93%)为男性,19例(7%)为女性。在本研究期间,男性声门型肿瘤的比例保持稳定,但女性有所增加。吸烟习惯的改变似乎是从声门上型肿瘤向声门型肿瘤转变的最重要原因。

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