Effect of vitamin A therapy on serologic responses and viral load changes after influenza vaccination in children infected with the human immunodeficiency virus.

作者信息

Hanekom W A, Yogev R, Heald L M, Edwards K M, Hussey G D, Chadwick E G

机构信息

Department of Pediatrics, Northwestern University Medical School, Chicago, IL, USA.

出版信息

J Pediatr. 2000 Apr;136(4):550-2. doi: 10.1016/s0022-3476(00)90024-6.

Vitamin A administered to children infected with the human immunodeficiency virus before influenza vaccination in a double-blind randomized study did not enhance vaccine serologic responses but did dampen the increase in the human immunodeficiency virus viral load 14 days after immunization (vitamin A, decrease of 0.13 +/- 0.09 log(10) copies/mL; placebo, increase of 0.14 +/- 0.08, P =.02).