巨细胞病毒引起的大量小肠出血。病例报告及文献综述。

Cytomegalovirus-induced massive small intestinal bleed. Case report and review of the literature.

作者信息

Sun J H, Johnson W S, Bascom J F

机构信息

Department of Surgery, University of Colorado Health Sciences Center, Denver.

出版信息

Rev Med Chir Soc Med Nat Iasi. 1997 Jul-Dec;101(3-4):209-12.

PMID:10756801

Abstract

We report a case of massive small intestinal bleeding in a non-HIV positive patient treated with cyclophosphamide and steroids for polyarteritis nodosa. Tagged red blood cell studies, endoscopy, and angiograms were performed prior to exploratory laparotomy. Jejunal ulceration and bleeding were evident by serosal staining. Resected segments revealed intracytoplasmic inclusions positive for cytomegalovirus by immunoperoxidase staining. A second bleed after the resection was controlled with oral norepinephrine, prior to effective therapy with ganciclovir.

摘要

我们报告一例非HIV阳性患者，因结节性多动脉炎接受环磷酰胺和类固醇治疗后出现大量小肠出血。在进行剖腹探查术前，进行了标记红细胞研究、内窥镜检查和血管造影。通过浆膜染色可见空肠溃疡和出血。切除的节段经免疫过氧化物酶染色显示巨细胞病毒胞浆内包涵体呈阳性。切除术后再次出血，在使用更昔洛韦进行有效治疗之前，通过口服去甲肾上腺素得以控制。